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How do Breakthrough COVID-19 Cases Happen?

Joe Gastaldo, MD, System Medical Director of Infectious Diseases at OhioHealth explains the trends in breakthrough cases.

Unsurprisingly, we are seeing breakthrough infections in people who are fully vaccinated. Antibody titers protect you most from infection. Fully vaccinated individuals have high antibody titers that naturally decrease over time.

With the delta variant, once your antibody titers get low, you have less protection against the infection. Most breakthrough infections in people are asymptomatic or someone with mild to moderate symptoms. Some breakthrough infections are being hospitalized, but it is often elderly people, those with weakened immune systems, and individuals vaccinated early in the vaccination process.

Want to learn more about common COVID-19 questions? Check our Fast Facts page.

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